Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (also known as SLE - Lupus Erythematosus) is an autoimmune disorder where antibodies are created against the body's own DNA.

The immune system becomes hyperactive and attacks normal tissue. In lupus, autoimmune attacks result in inflammation, which in turn brings about a variety of symptoms.


Like some other autoimmune diseases, it affects mostly women and its cause is unknown. It can present with a characteristic butterfly-shaped rash of the face, causing a wolf-like appearance (lupus is Latin for wolf).

Other symptoms include arthralgia (more often than frank arthritis), kidney damage (nephritis), blood coagulation problems (such as lupus anticoagulans), as well as effects on the central nervous system, lungs, heart and blood vessels.


Lupus is a chronic disease; there are some treatments for the symptoms, but no cure is known.

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