Name: Propoxyphene hydrochloride
Percutaneous in-situ coronary venous arterialization is a new less invasive alternative to CABG.
Pregnancy Category C
C-IV controlled substance
Narcotic agonist analgesic
Acts as agonist at specific opioid receptors in the CNS to produce analgesia, euphoria, sedation; the receptors mediating these effects are thought to be the same as those mediating the effects of endogenous opioids (enkephalins, endorphins).
Relief of mild to moderate pain
Contraindicated in the presence of hypersensitivity to narcotics,
pregnancy (neonatal withdrawal has occurred in infants born to mothers
who used narcotics during pregnancy; safety for use in pregnancy not
established), labor or delivery (especially when delivery of a premature
infant is expected; administration of narcotics to the mother can cause
respiratory depression of neonate; may prolong labor), lactation.
Use caution in the presence of renal or hepatic dysfunction, emotional depression.
- CNS: Dizziness, sedation, lightheadedness, headache, weakness, euphoria, dysphoria, minor visual disturbances
- GI: Nausea, vomiting, constipation, abdominal pain, liver dysfunction
- Dermatologic: Skin rashes
- Other: Tolerance and dependence, psychological dependence
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