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Brand Name: Cataflam
Name: Diclofenac sodium

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Pregnancy Category B

Drug classes
Antipyretic
NSAID Analgesic

Mechanism of action of Cataflam
Inhibits prostaglandin synthetase to cause antipyretic and anti-inflammatory effects; the exact mechanism of action is not known.

Indications of Cataflam

1. Acute or long-term treatment of mild to moderate pain, including dysmenorrhea
2. Rheumatoid arthritis
3. Osteoarthritis
4. Ankylating spondylitis

Contraindications of Cataflam

1. Contraindicated in the presence of significant renal impairment, pregnancy, lactation.
2. Use caution in the presence of impaired hearing, allergies, hepatic,
   cardiovascular, and GI conditions.

Adverse effects of Cataflam

• CNS: Headache, dizziness, somnolence, insomnia, fatigue, tiredness, dizziness, tinnitus, ophthamologic effects
• GI: Nausea, dyspepsia, GI pain, diarrhea, vomiting, constipation, flatulence
• Hematologic: Bleeding, platelet inhibition with higher doses
• GU: Dysuria, renal impairment
• Dermatologic: Rash, pruritus, sweating, dry mucous membranes, stomatitis
• Other: Peripheral edema, anaphylactoid reactions to fatal anaphylactic shock

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