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Date of last update: 8/21/2017.

Forum Name: Rheumatology Topics

Question: ANA 1:40 Speckled, Problems Swallowing, Shortness of Breath?

 LAT37 - Fri Sep 18, 2009 8:05 pm

I am a 33 year old female with a history of neurologic symptoms (Basilar Migraine, ataxia, anisocoria, numbness.) Lately, however, have had the following symptoms which seem to be unrelated:
Difficulty swallowing
Weight loss (from 126 to 110 in 6 weeks)
Shortness of breath (severe)
Raynaud's Syndrome (rarely, but always in the toes.)

Recent bloodwork showed the following:
ANA Positive, 1:40, speckled, RH neg, Sed rate: 2.

Is this worth pursuing as a possibility of an auto-immune related disorder? I would very much appreciate any advice you could give on this matter. Thanks so much.
 Tom Plamondon PA-C - Sun Sep 20, 2009 9:21 pm

User avatar Hello,
Systemic sclerosis can cause problems with swallowing, weight loss, respiratory difficulties and Raynaud's.
So yes, it is worth a more in depth evaluation including antibody testing through the rheumatologist.

Take care.
 LAT37 - Mon Sep 21, 2009 1:04 pm

Thanks so much for the reply. My GP stated that 1:40 is not significant, which I understand is usual, but in the face of the other symptoms I'll follow up with a rheumatologist.
Thanks again!
 LAT37 - Fri Oct 23, 2009 10:23 am

Rheumatologist found a high positive for Sjogrens.

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