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Date of last update: 8/13/2017.

Forum Name: Urinary tract infections

Question: Urinary tract infections - kidney transplant

 ignore - Thu Jan 29, 2009 12:16 pm

My mother is a kidney transplant, 3 years ago she had a stroke in her spinal cord and she lost her sensation and lost bladder control , but with intensive rehabilitation, she is now able to feel her lower half, yet she lose control of her bladder. Furthermore she is having repeated Urinary tract infections and each time she has been treated by taking antibiotics; my concern is that her body will resist antibiotics in the future, what could be the alternative treatment for her situation.
 Dr. Chan Lowe - Sat Jan 31, 2009 11:29 pm

User avatar Hello Ignore,

Your mother may wish to discuss the benefits of beginning a prophylaxis regimen to help prevent urine infections if she is having a lot of them. This basically is taking a low dose antibiotic every day to help prevent the infection from starting. This strategy can be very effective in the right situations. There is a small risk of developing a resistant bacterial infection; however, with the antibiotic present in the urine it will serve to keep bacteria from establishing a presence and subsequently being able to become resistant.

You are correct that repeated antibiotics can lead to resistance. Resistance develops the most quickly when antibiotics are used inappropriately, such as not finishing a prescribed course. This gives the bacteria a chance to recover after they have been exposed to the antibiotic but not yet killed by it. The idea behind prophylactic antibiotics is to keep the bacteria from getting into the urine and having a chance to become resistant.

While this works well, there are occasional breakthrough infections in some people and this may subsequently be a reason to change or stop prophylaxis. A urologist or her nephrologist would be the best doctors to talk with about this.

Best wishes.

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